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To the best of our knowledge, this is the first report on a basic, 3D-structural effect on cellular stability and function.
The most significant advantages of immobilized yeast cell systems are the ability to operate with high productivity at dilution rates exceeding the maximum specific growth rate, the increase of ethanol yield and cellular stability and the decrease of process expenses due to the cell recovery and reutilization (Lin and Tanaka2006).
With regard to their cellular stability and lifetimes, ordered and disordered proteins behave similarly.
n-Butanol shock experiments revealed that E. coli BT12 showed a higher cellular stability and tolerance under an extreme lethal n-butanol concentration.
The amount and steric properties of starch granules influence tuber starch content, which correlates with specific gravity [ 29] and thereby affect cellular stability and tuber bruising.
Because the nucleus is the largest mechanosensitive organelle, it would also be interesting to examine alterations of nuclear mechanical properties and stiffness caused by P1 deficiency and their consequences for cellular stability and function.
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Nuclear PTEN has a role in chromosome and cellular stability, DNA repair, and cell cycle arrest.
Intestinal barrier function is complex and its control involves cellular stability at a cytoskeletal and tight junction level, as well as mucus, chloride and water secretion.
In multicellular organisms, cells must be responsive to systemic cues of the physiological state to maintain energetic and cellular stability in addition to sensing the immediate environment.
To investigate the relationship between the structural architecture of proteins and their cellular stability, we inferred the disorder status of every residue in the proteomes of yeast, mouse, and human using the DISOPRED2 (Ward et al., 2004), IUPRED (Dosztányi et al., 2005), and PONDR VLS1 (Obradovic et al., 2005) software.
Similar cellular stability was observed for enhanced green fluorescent protein (EGFP).
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CEO of Professional Science Editing for Scientists @ prosciediting.com