The results showed that the dimensionless cellular size was proportional to We−0.5, which were in good agreement with the experimental results.
Three different populations corresponding to healthy (H), early apoptotic (EA) and late apoptotic (LA) could be identified according to the degree of Cyt c release and cellular size.
The increased heterogeneity of the cellular size was obvious in cell suspension (Figure 2, upper panel), and was further confirmed and quantified by flow cytometry (Figure 2, lower panel).
The field emission scanning electron microscopy images revealed that both wild type and M2, though combating toluene stress, did not have any significant changes in their cellular size and shape.
This method compared the relative glycan expression profiles of cell lines whose cellular size and character might not be uniform; therefore, we normalized the staining signal by using the ratio of the stained sample MFI to the control MFI.
At 16 20 wks p.i. the premalignant phenotype became much more evident, such that experimental animals displayed increased cellular size and nuclear atypia, as well as abnormal cellular morphology of luminal epithelial cells (Figure 1A iv)).
Activated Rho GTPases bind to and activate several downstream effectors, leading to multiple biologic processes, such as cellular size, cell cycle progression, apoptosis, survival, morphology, cellular polarity, cellular adhesion, and membrane trafficking [20], [21].
Given the importance of Tsc-Rheb-Tor signaling in regulating cellular and tissue growth, it was important to determine if disruption of this pathway affects neural development via its effects on growth or through signaling components independent of those that govern cellular size and growth.
This may explain the correlation between vacuolarisation with cellular size.
An increase in cellular size is paralleled by an increase in nuclear and nucleolar size.
