Sentence examples for cellular signalling pathways from inspiring English sources

Hsp90 is a ubiquitous ATP-dependent dimeric molecular chaperone that plays a central role in cellular signalling pathways since it is essential for maintaining the activity of several signalling proteins including steroid hormone receptors and protein kinases.

This approach targets one of the core deregulated cellular signalling pathways in cancer, which is totally different from cytotoxic chemotherapy.

All these negative effects of absent enteral nutrition can be explained by a distinct change in cellular signalling pathways.

Several ligands including the growth factor pleiotrophin (PTN) bind to RPTPβ and inhibit its phosphatase activity, thereby activating cellular signalling pathways.

Recent studies have revealed that crucial cellular signalling pathways are regulated by the extra- and intracellular redox states and that reactive oxygen species function as intercellular signal molecules.

In a recent report [[13]] indicated that nanoparticles can damage DNA of cancer cells without actual penetration in the nuclear milieu and they perform such acts by invoking new cellular signalling pathways.

The interesting biological and structural diversity of this class of substances makes it a particularly interesting template for the design of compound libraries in search of small molecules that effect cellular signalling pathways.

G protein-coupled receptors (GPCRs) represent one of the major targets of new drugs on the market given their roles as key membrane receptors in many cellular signalling pathways.

More recent findings have shown that LDL receptor family members can also function as direct signal transducers or modulators for a broad range of cellular signalling pathways.

There are pronounced changes in calcium-dependent intra cellular signalling pathways after CNS injury.

An intriguing possibility is that cellular signalling pathways use this domain to influence mRNA cap methylation.