Sentence examples for cellular sensor for from inspiring English sources
Keap1 protein acts as a cellular sensor for oxidative stresses and regulates the transcription level of antioxidant genes through the ubiquitination of a corresponding transcription factor, Nrf2.
The p53 tumor suppressor plays a central role in dictating cell survival and death as a cellular sensor for a myriad of stresses including DNA damage, oxidative and nutritional stress, ischemia and disruption of nucleolar function.
Vanin 1was described as a cellular sensor for oxidative stress that orchestrates the innate immune response [37].
Moreover, these findings support the idea that the function of TLRs extends beyond host defense against invading pathogens; TLR4 seems to be a cellular sensor for acute renal damage that controls innate immunity and tissue integrity.
Key factors for antioxidant enzyme induction are nuclear factor-E2-related factor-2 (Nrf2), a transcription factor that serves as a cellular sensor for oxidative stress [64], [65], and PGC-1α [66].
While mTOR was presumed to serve as the direct cellular sensor for ATP levels [17], mounting evidence has implicated AMPK in the regulation of mTOR activity [15], [18] [20].
The TRP family of cation channel proteins has been served as cellular sensors for detecting an array of environmental stimuli [ 31].
It appears that a common cellular sensor monitors the need for ECM remodelling and regulates the balance between heparanase and MMP expression.
This simple technology may be used to create reconfigurable interfaces that allow users to selectively discard contaminated or exhausted cellular sensor elements, and to replace them with new living cellular components for continued operation in future biomedical microdevices and biodetectors.
The serine/threonine protein kinase AMPK is a cellular energy sensor for glucose and lipid metabolism regulating the cellular energy balance.
The next step involves identifying the cellular sensor(s) that recognize the unfolded protein as well as the transcription factors that are responsible for increasing gene expression.
