The new Aibo sports a whole host of enhancements to connectivity (both WiFi and cellular), sensors, and AI (that enables Aibo's lifelike behavior to mature over time).
Chemopreventive Nrf2 inducers affect the interaction between Keap1 and Nrf2 through several mechanisms such as redox-sensitive modifications on cysteine residues of Keap1 or other cellular sensors and phosphorylation of Nrf2 [36].
Instead, synthetic genetic logic circuits can be introduced through linking various cellular sensors and genetic actuators, to achieve customized cellular responses (Kobayashi et al., 2004) and sensing abilities (Khalil and Collins, 2010) in a designed and logical manner.
We describe the underlying principles, methodology, and preliminary results of modelling and simulating a multi-cellular sensor and communication network in a dynamic decentralised setting, motivated by a self-monitoring, self-repairing AAV.
This simple technology may be used to create reconfigurable interfaces that allow users to selectively discard contaminated or exhausted cellular sensor elements, and to replace them with new living cellular components for continued operation in future biomedical microdevices and biodetectors.
The protein kinase mTOR functions as a cellular sensor of nutrient and energy availability, and regulates cell growth and autophagy.
It is a cellular sensor of chemical- and radiation-induced oxidative and electrophilic stress, and a nuclear transcription factor that controls the expression and coordinated induction of a battery of defensive genes encoding detoxifying enzymes and antioxidant proteins.
Nrf2 is a cellular sensor of chemical- and radiation-induced oxidative and electrophilic stress [ 30] and controls the expression and coordinated induction of a battery of defensive genes encoding detoxifying enzymes and antioxidant proteins.
Collectively, these data suggest that Hsp90, specifically Hsp90α, functions as a cellular sensor of ATP and does so by directly interacting with F1F0 ATP synthase.
Here, we present data showing an unrecognized link between DNA modifying enzymes, TETs, a master cellular sensor protein, OGT, and a histone modifying complex, SET1/COMPASS.
