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Because even small changes in cellular energy state may initiate cellular pathology and death, fast reacting PMCA2 and PMCA3 isoforms may be considered as cellular bodyguards protecting against Ca2+ overload and subsequent mitochondrial failure.
Glucose not only provides energy and anabolic materials but also sustains a reducing cellular environment, protecting cells from oxidative stress.
which are assumed to function as cellular chaperones protecting cells from heat shock and regulating cell growth and acute allergic response.
Induction of heat shock proteins is a critical and highly conserved cellular response protecting cells from a range of stresses including damage caused by normal physiological processes, extreme environmental stress or disease.
Superoxide dismutases act as part of the cellular antioxidant system protecting the redox sensitive cellular machinery from damage induced by reactive oxygen species (ROS).
How to cite this article: Perić, M. et al. Crosstalk between cellular compartments protects against proteotoxicity and extends lifespan.
A new study shows how cellular "housekeeping" protects some neurons against the toxic proteins of Alzheimer's disease and suggests new treatment possibilities.
Free glutathione (GSH) being the quencher of cellular ROS protects the cells and tissue from ROS mediated damage.
A small portion of LDHB may localize to other cellular locations protected against cytosol removal.
An increase in cellular cAMP protects hypoxemic induced endothelial injury by preserving its barrier function [ 5], and improves post-ischemic recovery in the liver and kidney [ 6, 7].
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