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When we performed functional analyses of ECT2 in OSCC-derived cells using the shRNA system, the cellular proliferation of the ECT2 knockdown cells decreased significantly compared with the control cells (p<0.05).
Therefore, cellular proliferation of the Leydig cells may be induced by ELF-MF exposure at relatively early phase.
This partial reduction in PR-SET7 did not affect cellular proliferation of the MEFs (data not shown).
Preclinical studies involving 17-AAG revealed that it reduced cellular proliferation of the trastuzumab-resistant cell line JIMT-1 [ 83].
Pterygium is an inflammatory and degenerative process resulting from an uncontrollable cellular proliferation of the subconjunctival and fibrovascular connecting tissue on the cornea.
In this study, we found that S6K1 knockdown is more effective than GLI1 knockdown in reducing the cellular proliferation of the non-MYCN amplified SK-N-AS cell line.
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The results demonstrated that the overexpression of BMP-RII increased the cellular proliferation of LNCaP cells in the absence of androgens.
MTT assay was performed to study the cellular proliferation of neuro 2a in the presence of α-KG, when administered by three different modes as described previously in the methods section.
The effects on cellular proliferation of Pep-7 obtained using the MTT assay indicated that it significantly inhibited the viability of HPV16-positive cervical cancer cells.
The results demonstrated a significant reversal of the cellular proliferation of both LNCaP and 22Rv1 when BMP-6 was blocked.
Notwithstanding, these results collectively demonstrate that ALK2 and BMP-RII are the optimal types I and II receptors that mediate cellular proliferation of CaP cells in the absence of androgens.
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