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The simple method for predicting cooperative drug effects confirms the potential predictive ability based only on the quantitative cellular profiling of response to individual drugs.
In our study, we investigated whether cellular responses of drug combinations can be modeled quantitatively by the cellular profiling of response to individual drugs.
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In this study, immunohistochemical method was used to observe DMRT1 protein localization in order to resolve cellular profile of DMRT1 in the adult testis of three-spot wrasse.
The pattern of Pea3 expression in MMTV/Wnt1 mammary glands recapitulated the cellular profile of activated β-catenin/TCF signaling, which was visualized using both β-catenin immunohistochemistry and the β-catenin/TCF-responsive reporter Axin2NLSlacZ.
The cellular profile of epithelial lining fluid (ELF) changes with age.
To evaluate the area of the cellular bodies (cellular profile) of myenteric neurons, 500 neurons per group were measured.
The score recorded for a given wound reflected the predominant cellular profile of the tissue within the wound void.
The extent and cellular profile of the infiltrate was correlated with the transformation level that was established by morphology and p53 expression of the epithelium.
Examination of cellular profile of induced sputum, a standard in some adult cough clinics, can only be performed in older children (children >6 years).
To estimate the magnitude of airway inflammation, we examined the cellular profile of BAL fluid 24 hr after intratracheal instillation (Table 1).
Moreover, the cellular profile of DNA hypermethylation has been implicated in progression and metastasis of lung cancer (Nakamura et al, 2003; Shimamoto et al, 2004).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com