Sentence examples for cellular pathways such from inspiring English sources

Our work unveils the signaling pathways involved in the interaction of GO-PEG-PEI with mammalian cells, and highlights the necessity and importance of comprehensive investigations of the effects of nanomaterials on cellular pathways, such as the cell cycle in this case, even for those with seemingly little/low cytotoxicity during preliminary evaluations.

The WD repeat proteins are involved in diverse cellular pathways, such as signal transduction, pre-mRNA splicing, transcriptional regulation, cytoskeletal assembly, and vesicular traffic [25], [26].

Select genes associated with rare familial forms of PD function in cellular pathways, such as the ubiquitin-proteasome system (UPS), involved in protein degradation.

Proteins with domain-altering SNPs comprise highly connected nodes in cellular pathways such as the focal adhesion, the axon guidance pathway and the autoimmune disease pathways.

The inhibitors of other cellular pathways, such as HSP90 and NF-κB, known to be affected by Celastrol, had no such effect.

Specificities in cell-type response to neisserial infection was also described for other cellular pathways such as membrane shedding upon gonococcal infection, which is seen with ME180 cells but could not be observed on Hep2 cells [22].

Glucagone like Peptide-1 enhances the secretion of insulin from pancreatic beta cells following meals, as well as prevent apoptosis of these cells via sub-cellular pathways such as JNK [ 5].

CNT-induced oxidative stress mediates important cellular processes including inflammation, cell injury, apoptosis, and activation of cellular signaling pathways such as MAPK and NF- κB which are implicated in the pathogenesis of lung fibrosis [ 31, 117].

Growing evidence has indicated that cellular redox plays an essential role not only in cell survival but also in cellular signaling pathways such as NF κB.

These enzymes, the Sirtuins, are localized in several cellular compartments and are key regulators of energy metabolism, gene function and also interface with several key cellular signalling pathways such as the cAMP PKA, AMPK and mTOR (mammalian target of rapamycin) pathway [ 38, 39, 45].

In general, cancer-related gene sets, such as MYC and E2F targets and G2M, showed a "normal-like" tendency in NAT; normal cellular differentiation pathways, such as adipogenesis and myogenesis, showed a "gradient" tendency; and inflammatory-related pathways showed a "tumor-like" tendency (Fig. 4b).