Sentence examples for cellular pathways responsible from inspiring English sources
Our recent efforts have focused on defining the cellular pathways responsible for viral entry and infection into renal epithelial cells using herpes simplex virus (HSV) as a model vector.
While the morphological development of these cells must be tightly regulated, the cellular pathways responsible are still largely unknown.
The precise cellular pathways responsible for ADI-PEG20-induced cell death seem to be variable, and have not yet been fully elucidated (Bursch et al, 2008; Kim et al, 2009a; Savaraj et al, 2010).
The study of neuronal remodeling after injury in model organisms has elucidated cellular pathways responsible for morphological changes, however, little is known about the molecular cues that initiate these cascades.
The UCHL1 enzyme is involved in the ubiquitin proteasome system, a cellular pathway responsible for the degradation of misfolded and damaged proteins (6).
While we agree that it is important to figure out which cellular pathways are responsible for successful incretin therapy, we do not feel that most clinical trials are effective tools to do so.
The focus of this work, therefore, deals with examination of the cellular signaling pathways responsible for TiO2 NP-induced endothelial oxidative stress and inflammation.
However, other cellular pathways are also responsible for regulating miRNA expression.
ROP16 alleles differentially affect cellular signal transduction pathways responsible for inflammation in vivo (Saeij et al., 2007) and have some impact on virulence (Saeij et al., 2006), while a virulence QTL on Chromosome XII embraces the ROP5 locus (Saeij et al., 2006).
Prompted by the observation that overall ROS levels were 'normal' during chronic infection but the apoptotic subpopulation showed oxidative stress, we investigated the cellular antioxidant defence pathways responsible for compensation to the chronic infection and the adaptational failure(s) associated with progression to apoptosis.
The exact cellular and molecular pathways responsible for LV remodeling are still unclear, although a key event is myocyte lengthening and stretch, stimulated expression of altered proteins and myocyte hypertrophy, leading to a further deterioration in cardiac performance and increased neurohormonal activation.
