Sentence examples for cellular pathways relevant from inspiring English sources

RB1CC1 plays complex roles in cellular pathways relevant to carcinogenesis [27].

The functional inactivation of p53 and pRb oncosuppressors by E6 and E7 oncoproteins determines the alteration of several cellular pathways relevant for cell transformation and cancer development.

Therefore, Drosophila has emerged as a powerful model system for the elucidation of fundamental cellular pathways relevant to both intestinal stem cell biology and to aging.

To uncover cellular pathways relevant for intoxication we used genome-wide analyses in a yeast model system and identify fourteen genes that, if deleted, result in higher polyglutamine toxicity.

A large number of publications in recent years has shown that physiological quantities of resveratrol can modulate multiple cellular pathways relevant for tumorigenesis, among them phase II drug metabolizing, cyclooxygenase, nitric oxide, DNA-synthesis, and inflammatory response, as well as cell survival, cell death and cell cycle pathways [ 2].

The reasons for this toxicity and the cellular pathways relevant for this process are under debate and many alterations have been reported, including DNA-fragmentation, apoptosis, spindle disorganization and involvement of the chaperone system or diverse prion proteins [ 20, 23, 24, 26].

He hopes to pursue projects such as developing therapeutics with chemists, working with biophysicists to study protein conformational changes relevant to viral entry into the cell, and investigating cellular trafficking pathways relevant to the viral life cycle in collaboration with cell biologists.

Regardless of platform differences, the three miRNAs identified by both platforms, let-7d, miR-203 and miR-320, hold promise as tubular injury biomarkers due to their strong functional associations with cellular process or pathways relevant to renal disease.

Histone deacetylase 6 (HDaC6), a member of the class II HDAC family, is unique in being predominantly cytoplasmic (Verdel et al., 2000), which served as an early indication of the vital roles of HDAC6 in regulating lysine acetylation and relevant cellular pathways in the cytoplasm.

In recent years, miRNAs have been identified as key regulators of protein expression and have been implicated in many physiologically relevant cellular pathways [8].

Interestingly, deregulation of many relevant cellular pathways has also been shown in those patients with higher percentages of 13q deletion (above 80%).