Sentence examples for cellular pathways known from inspiring English sources

But the cellular pathways known to transduce these signals are few [22], and Ca2+ signalling has been only partially characterized in embryonic stem cells [23].

These studies have led to identification of genes related to multiple cellular pathways known to be involved in AD pathogenesis and progression.

One possible way to promote extended survival of transplanted embryonic neurons is to enhance the activity of cellular pathways known to mediate cell survival signals, and the ability of neurons to extend neurites into surrounding tissues.

One approach to identifying a potential therapeutic agent would be to evaluate the effects of agents that can block cellular pathways known to be pathophysiologically linked to the development of infection induced muscle dysfunction [ 3].

Keytruda, manufactured by Merck, is designed to block a cellular pathway known as PD-1, which hinders the immune system's ability to attack melanoma cells.

Angiogenesis depends upon the activation of a cellular pathway known as PI3K/Akt, but identifying nontoxic compounds that can inhibit this pathway has proved tricky.

In other words, we predict that a candidate gene for CIN in a tumor will typically belong to a cellular pathway known to cause CIN in model organisms.

Very recently, we also reported that Neu5Gc loss in the heart, lung, and kidney of Cmah-null mice affected the complex regulation of cellular signaling pathways known to be involved in human diseases [ 17].

This period of increasing mutualism among still-separate cells also allows time for ever more complex inter-cell communication and regulatory pathways to evolve, building on the inter-cellular chemical communication pathways known to exist in biofilms [ 157, 208, 265– 267].

Dihydrofolate reductase (DHFR) and thioredoxin reductase (TrxR) are enzymes belonging to two unrelated cellular pathways that are known to contribute towards cancer cell growth and survival.

Moreover, this activity of 5-azacytidine depends on the induction of MYC expression, thus providing a link between the effect of this drug and one of the key cellular pathways that are known to affect NMD activity.