Sentence examples for cellular pathways implicated from inspiring English sources

Joseph, MI, USA) was used to identify the cellular pathways implicated by genes regulated in the estrous cycle and dysregulated in ovarian cancer and to examine whether gene ontologies were statistically over-represented in these gene sets.

EDNR antagonists have been proven as potent and specific ET-axis inhibitors that block cellular pathways implicated in tumour growth.

One inescapable observation, evident from even a cursory look at the genes mentioned in the preceding sections, is the apparent range of cellular pathways implicated in the pathogenesis of dystonia.

Future studies should be directed at understanding the interaction between sepsis and mechanical ventilation, and to developing therapeutic approaches that target their common cellular pathways implicated in diaphragmatic weakness.

Using this MCF7 system we carried out microarray experiments that revealed the absence of TopBP1 alters the expression of genes involved in many cellular pathways implicated in breast cancer, including the oestrogen signalling pathway, and the mitogen-activated protein kinase signalling network.

Our model could be further validated by future experimental studies testing, for example, different scenarios of T-cell viability assays (involving e.g. cellular pathways implicated in the control of cell death and survival, such as Jak/Stat, Ras/MAPK, PI3K/AKT, and interleukin signaling).

A mechanistic understanding of CIN in each mutant is not currently available; however, in many cases a simple hypothesis can be generated to explain the role of a particular cellular pathway implicated in genome integrity.

The survival pathways implicated in cellular response to drug treatment are primarily PI3K/Akt and Ras/MAPK, which also mediate the signalling activated by growth factors and play a role in the regulation of critical processes including cell proliferation, metabolism, apoptosis and angiogenesis.

miRNAs regulate the expression of the majority of protein coding genes in the human genome, thereby affecting most biochemical pathways implicated in cellular homeostasis.

Phosphorylation of ITAM/ITIM initiates of terminates, respectively, signal transduction pathways implicated in cellular proliferation (Beauchemin et al. 1997) or regulation of immune response.

The 31 discriminating phosphopeptides represented proteins derived from signaling pathways implicated in various cellular processes, such as proliferation, angiogenesis, and invasion.