Sentence examples for cellular pathways contributing from inspiring English sources

To identify the other potential cellular pathways contributing to TAIII cytotoxicity in tumor cells, we examined the functional role of Id-1 that, along with Id-3 is strongly downregulated in breast cancer cells but not in MCF10A (Figure 3A and Table S2).

Moreover, there is a paucity of functional modeling of known variants that could be used to draw putative molecular and cellular pathways contributing to AF symptoms.

Identification of such precursors may identify cellular pathways contributing to both the blood-borne dissemination of cancer and processes involved in metastatic colonization.

Upcoming larger migraine GWA studies, across different ascertainment schemes, are likely to identify more genes and cellular pathways contributing to migraine susceptibility and will hopefully also shed light on the potentially different genetic background of different migraine subtypes.

Genes encoding adaptor and mediator molecules of the TLR activation pathway were also profiled by real time qRT-PCR to examine cellular pathways contributing to the differential response between BTB-infected and control animal groups.

The combination of expression profiles of relevant cell models, which can be manipulated in vitro, and high-quality specimens from patients might permit the identification and understanding of the important cellular pathways contributing to major clinical features of malignant diseases [ 43].

In addition to publication in peer-reviewed journals, recent expansion of the KEGG database of cellular pathways contributed moderately to improved annotation.

The actions of aging proteins like TP53 on CVD have been well studied [ 83] and suggest that TP53 and its cellular pathways contribute to disease pathogenesis.

The majority of lysosomal disorders are characterized by intralysosomal accumulation of unmetabolized substrates; however, secondary alterations in other biochemical and cellular pathways contribute to a wide range of clinical symptoms (Futerman and van Meer, 2004).

Succination targets multiple proteins encompassing diverse cellular pathways, potentially contributing to the oncogenesis in FH-deficient tumors.

This represents a novel and significant cellular signalling pathway contributing to the cytotoxicity of NPs.