Sentence examples for cellular pathways associated from inspiring English sources

This software exploits a highly comprehensive database established from the literature to determine direct and indirect interactions between genes of interest, thereby identifying cellular pathways associated with a particular set of genes.

We compare intersecting gene expression profiles following separate PAR2 activation by a peptide (2f-LIGRLO-NH2) versus a serine protease (trypsin), expecting that genes up- or down- regulated by both agents might help identify cellular pathways associated with PAR2 activation.

Over the past decade, clinical research on HNSCC has focused on improving the efficacy of current multimodal approaches and decreasing toxicity by targeting cellular pathways associated with carcinogenesis.

Recently, molecular research has significantly improved our understanding of glioma pathogenesis and identified key proteins that regulate normal biological processes and cellular pathways associated with pediatric HGG.

PM such as DEP can up-regulate cellular pathways associated with free radical production (Donaldson et al. 2003, 2005), but few studies have looked at the innate ability of DEP to generate free radicals itself.

In addition, PGE2 can increase tumor growth by binding to G protein-coupled membrane receptors (EP receptors) leading to the activation of several cellular pathways associated with proliferation, migration, survival and angiogenesis.

In addition, the nature of the cooperating events in the L-GMP, identified by comparing signatures from Day 10 AML1-ETO-induced GMP and L-GMP from overtly leukaemic animals, fit with patterns expected from numerous studies, implicating cellular signalling pathways associated with transformation, survival and proliferation as critical for cooperation with AML1-ETO signalling.

In terms of clinical relevance, they provide information regarding the cellular "toolbox" e.g., pathways associated with malignancy and metastasis or drug dependency.

The data from complementary approaches were useful to allow the identification of molecular players and to outline the biological functions, cellular processes and pathways associated with the drupe defence reaction.

Although additional research is needed to fully elucidate the cellular and molecular pathways associated with the neuroprotective consequences of HDAC6 inhibition, it is becoming increasingly apparent that modulating HDAC6 activity may offer a very promising avenue for the treatment of AD and associated tauopathies.

NF-κB is a key transcription factor that is activated by several cellular signal transduction pathways associated with the regulation of cell survival and the expression of proinflammatory cytokines and enzymes such as iNOS, IL-6 and TNF-α [ 40, 41].