Sentence examples for cellular pathways altered from inspiring English sources

We also investigated cellular pathways altered in FD, at the genome-wide level, and confirmed that cell migration and cytoskeleton reorganization were among the processes altered in FD.

On the other hand, these cell lines share same cellular pathways altered, both harboring p14arf/p16 deletion and phosphatase and tensin homolog (PTEN) mutation.

Isolated from patients, cultures of hOE-MSCs provide potential models for genetically determined neuropsychiatric diseases [31] [33], and stand as an interesting human model to investigate gene networks and cellular pathways altered in disease like FD.

The ubiquitin-proteasome signaling [ 8, 10, 11], Ca2+-dependent proteolysis [ 12] and/or calpain-mediated proteolysis [ 6, 13, 14] have all been proposed to play a role, however the molecular and cellular pathways altered following β-AR agonist administration remain poorly understood [ 15].

At least 19 cellular pathways were altered in the S18-2-immortalized cells (Table 1).

But also other genes, such as cytokine receptors and regulators of other cellular pathways are altered during passaging (Table 1).

These results suggest that a complex web of cellular pathways become altered in Ad-transformed cells and that Ad E1A is sufficient for the observed dysregulation.

Bioinformatic analyses suggested that DF-1 cells were characterized by enhanced molecular mechanisms for cell cycle progression and proliferation, suppressing cell death pathways, altered cellular morphogenesis, and accelerated capacity for molecule transport.

Among the 67 factors, 40 principal components are required to account for 95% of the observed variability (supplementary figure S2) implying that a relatively high biological "dimension" underlies the 67 factors – they reflect a diverse set of biological activities, and presumably pathways altered in the cellular responses to lactic acidosis within human breast tumors.

Biological pathways altered in the current study included: cellular growth and proliferation, lipid metabolism, tissue remodeling, ECM mineralization, inflammation, angiogenesis, and metabolic exchange.

Future studies looking at the cellular pathways that are altered, as well as the genes upstream and downstream of these pathways, will be necessary.