Sentence examples for cellular pathogenic from inspiring English sources

This result suggests that UPR activation may be a conserved cellular pathogenic mechanism in myocarditis that is caused either by viral infections or autoimmune responses.

Previously, a number of different cellular pathogenic mechanisms have been suggested for SPG15 and SPG11: defective DNA repair, cell division abnormalities, endolysosomal dysfunction, and impaired autophagy.

12– 15 However, additional prospective studies are needed to elucidate other risk factors and molecular and cellular pathogenic mechanisms, discover new pharmacologic agents, improve eye health, and preserve better vision and quality of life.

In terms of its immunomodulatory effects, pitavastatin has been shown to inhibit the production of interferon-α and TNF-α by human plasmacytoid dendritic cells, which are key molecular and cellular pathogenic components in autoimmune diseases.

The underlying cellular pathogenic mechanisms resulting in these cardinal hallmarks of the disease are not completely understood and even less is known about other types of AD-related neuropathology such as the early intracellular accumulation of GVD (granulovacuolar degeneration) bodies, a feature not only of AD but also other neurodegenerative diseases (Okamoto et al., 1991).

We elucidated here the crucial roles of inducible and ectopic host cellular trypsins in the pathogenesis of IAV infection-induced acute myocarditis and found that aprotinin administration and selective trypsin-knockdown effectively suppress up-regulation of cellular pathogenic factors induced by IAV infection, such as trypsins, MMPs, and cytokines, resulting in the improved cardiac function.

However, this approach suffers from frequent complications, including the progressive occlusion of the tympanostomy tubes' lumen by cellular debris, pathogenic bacterial films, ear wax, blood and pus.

Several mechanistic studies were undertaken to determine the cellular source providing pathogenic TNF loads as well as the cellular targets of pathogenic TNF.

Although both cytokines are implicated in PsA, a full picture of their cellular targets and pathogenic mechanisms has not yet emerged.

Sumoylation is a highly dynamic process that is regulated in response to cellular stimuli or pathogenic challenges.

Our lab is focused on understanding the cellular and molecular pathogenic mechanisms underlying the dry and wet forms of AMD.