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Finally cellular packing density is increased where it does not appreciably affect connection length.
Here it was shown that certain architectures for these networks optimize the total cost of the number of cells, connection length, and cellular packing density.
1D, 2. Connection length and cellular packing density will be considered together because both are related to the geometric arrangement of cells.
For each of the logic circuits, there is an architecture that minimizes the total cost of the number of cells, connection length, and cellular packing density while retaining the network's functionality.
For each n there exists at least one Complete n-RANC that minimizes the total cost of the number of cells, total connection length, and cellular packing density while retaining functionality.
To evaluate cellular packing density, mice were killed humanely 24 or 72 h after bortezomib treatment.
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Additionally, one has to consider the different cellular packing densities in various brain regions, which varied in relative units from 0.381 (cerebellum, Stratum moleculare) to 4,453 (dentate gyrus) in the adult mouse.
Using MCC established from colon carcinoma cell lines with differences in cellular adhesion and packing density, we observed greater penetration and cytotoxicity of anticancer drugs in loosely packed MCC [ 3].
As the FA measurement is thought to be the result of numerous factors at the cellular level, such as myelin thickness and axonal packing density (Beaulieu 2002), the relationship between FA and large-scale network function is still not fully understood.
At the cellular level, it is important to note that while dendritic branching, neuronal packing density, nuclear volume and neuronal size are also similarly altered in Mecp2-deficient mice and Rett syndrome patients, there does not appear to be any significant neuronal degeneration resulting from the absence of Mecp2.
Lower packing density can be assumed to be partially due to the disintegration of cellular material as indicated by the debris in the space between myelinated fibres.
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