Sentence examples for cellular models that from inspiring English sources

Furthermore, the complexity of the mutant CFTR maturation and turnover kinetics requires the use of advanced cellular models that closely recapitulate the properties of the most affected organs (lung, bile duct, pancreas, and intestine).

We have used cellular models that involve cell-to-cell contact, as this is known to be important in HIV-1 pathogenesis.

It is thus imperative to develop new cellular models that incorporate these aspects of the pathology.

Cellular models that are more representative of fatty acid partitioning within the human liver are required to help elucidate the causes and progression of NAFLD.

Translocation and uptake of nanoparticles can be addressed by cellular models that can also be divided in relatively simple models or more complex ones (Lefebvre et al. 2014).

This study for the first time defines precise criteria for the validation of direct caspase-activating compounds using specialized cellular models that is expected to accelerate the discovery of potential direct caspase activators.

Next, we were interested in establishing a cellular model that allows investigating the regulation of isoQC and CCL2 in astrocytes.

We mapped the genome-wide dynamics of chromatin marks in a cellular model that is dependent on the EWS-FLI1 fusion protein.

Taken together, we have successfully established a cellular model that will be of broad utilities to the molecular exploration of NSC senescence and aging.

Although we use a small set of enzymes here to perform a preliminary proof of principle, this experiment lays the foundation for a method of cellular modeling that will move toward an "omics" approach with potential predictive ability.

As villin is expressed and properly distributed only in differentiated IECs, we used a cellular model that enables an endogenous apical expression of this protein after differentiation (i.e., human colonic TC7 cells).