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The aim of this study was to establish an in vitro cellular model based on human colon carcinoma Caco-2, mucus-producing HT29, and Raji B cells in order to design a model that more accurately mimics the small intestinal epithelial layer.
Taken together, our proteomic exploration unraveled some major aging-related pathways of both known and novel players and showcased the potential to elucidate aging-associated molecular mechanisms with the help of our cellular model based on HU treatment of NSCs.
Our original cellular model, based on the EGFP-12xQ/N construct, was based on 12 tandem repetitions of the core Q/N region (aa 339 369) of TDP-43 (16).
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In this paper, we propose a new cellular automaton model based on the well known three-phase traffic theory.
To investigate the suitability of the present lentivirus vector-based inducible reporter gene system to detect and quantify cell fusion events we exploited an ex vivo cellular differentiation model based on human myoblasts.
Supplementation of deoxycytidine (dCtd) has been shown to prevent mtDNA copy number reduction in a cellular MNGIE model based on thymidine-induced mtDNA depletion.
The objective of this study was to establish a conceptual cellular interaction model based on a recently established graph network to describe the interaction between two types of cells.
In summary, we describe a highly reproducible cellular AD model based on human iPSC-derived cortical neurons that enables the mechanistic analysis of A β-induced synaptic pathomechanisms and the development of novel therapeutic approaches.
In addition to testing of toxicity on cellular level, we decided also to investigate in greater detail the molecular mechanisms of action of studied complexes using the cellular model system based on the LPS-activated respiratory burst in phagocytes and its effect on the inflammatory cytokine expression.
The 2020 land use/cover was predicted using Markov Chain and Cellular Automata models based on 2006 and 2013 land use/covers.
The Runoff Model Based on Cellular Automata (RunCA) has been developed to simulate surface runoff at different scales by integrating basic cellular automata (CA) rules with fundamental measureable hydraulic properties.
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