Sentence examples for cellular mechanisms regulating from inspiring English sources
Inflammation is an important regulator of osteoarthritis (OA), but the molecular and cellular mechanisms regulating this process are not well defined.
Key areas of our research are the molecular & cellular mechanisms regulating heart (metabolism in cv disease), autocrine-paracrine pathways (modulating cardiac cell signaling and function), and metabolic signaling pathways in atrial fibrillation.
Immunofluorescence studies show that Spn4A is localized in the endoplasmic reticulum (ER), suggesting that the inhibitor is an interesting tool for investigating the cellular mechanisms regulating furin and for the design of agents controlling prohormone convertases.
Current projects are using a variety of approaches – including targeted gene knockouts to assess the function of transcription factors and stem cell factors, and single cell RNA sequencing – to elucidate the molecular and cellular mechanisms regulating olfactory stem cells and olfactory neurogenesis in the mouse.
I have found novel molecular and cellular mechanisms regulating adult neural stem cell quiescence and persistence (Zhou et al., 2018), division, fate decision (Sun et al., 2015a), and newborn neuron migration (Sun et al., 2015b).
The cellular mechanisms regulating Nm23 functions are poorly understood.
To this end, we identified both known (Wnt-β-catenin) and novel (cell adhesion and MAPK/ERK) cellular mechanisms regulated by mesalamine using differential gene expression analysis.
Specifically, although previous work characterizing this important oncogene in cell culture and mice has provided valuable information, the zebrafish could provide a more relevant in vivo developmental model for this gene in which key questions regarding the molecular and cellular mechanisms regulated by etv7 can be addressed.
Not only do they give a first insight into the cellular mechanism regulating blood distribution in the brain, he says, they also reveal the basic process that's depicted as brain activity by routine brain scans.
Intracellular Ca2+ concentration, a key cellular mechanism regulating cell proliferation and death, is mainly mediated by the plasma membrane associated voltage-gated ion channels as well as the RYR and ITPR channels on the ER.
Finally, they discuss the potential origin of this self-regulatory ability in the wider context of developmental and comparative biology with emphasis on a putative "diversification factor", defined as a cellular mechanism regulating the adaptation of aneuploidy rates, which is active in all embryonic and adult cells, as well as cancer stem cells.
