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They involve in various cellular mechanisms including development, differentiation, proliferation, and apoptosis.
WS is caused by mutations in the WRN gene, which is involved in several fundamental cellular mechanisms, including DNA replication, DNA repair, and telomere maintenance (Burtner and Kennedy, 2010; Kudlow et al., 2007; Lopez-Otin et al., 2013).
We simulate cellular mechanisms including cell adhesion, growth, and division and diffusion of morphogens, to show that differential adhesion between the cells, diffusion of growth factors through the extracellular matrix, and the elastic properties of the apical ectodermal ridge together can produce the proper shape of the limb bud.
Regulation of microtubule dynamics underlies many fundamental cellular mechanisms including cell division, cell motility, and transport.
Nr4a3/Nor1 is thought to be an important regulator of cellular mechanisms including apoptosis.
More than 50 putative γ-secretase substrates have been identified which regulate a variety of cellular mechanisms including inflammation, development, and synaptic plasticity [1].
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However, most cellular mechanisms include natural fluctuations that are closely regulated, and thus lead to asynchronization of the cells, which causes intrinsic heterogeneity in a given population.
Other possible cellular mechanisms include the effects of gabapentin on NMDA receptors, sodium channels, monoaminergic pathways, and the opioid system [ 2– 5].
To protect themselves from adverse conditions, plants have evolved a number of cellular defense mechanisms including antioxidants such as ascorbate, glutathione and tocopherols as well as ROS-detoxifying enzymes such as superoxide dismutases, peroxidases and catalases (Inzé and Van Montagu 1995; Noctor and Foyer 1998).
This study was designed to investigate whether -epigallocatechin-3-gallate (EGCG) plays a neuroprotective role by inhibiting nitric oxide (NO) production and activating cellular signaling mechanisms including MAP kinase, PI3K, and GSK-3β and acting on the antiapoptotic and the proapoptotic genes in N18D3 neural cells.
This stress could reduce growth activity and turned on cellular protection mechanisms including glutathione biosynthesis [ 29].
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