Sentence examples for cellular mechanisms affecting from inspiring English sources

Traditional chemotherapy targets general cellular mechanisms, affecting normal cells as well as tumour cells.

Ease of transmission of prions between species (or also within species as a result of PrP polymorphisms), therefore, relates to overlap of permissible PrPSc conformations between the structures of PrP from the source and recipient as well as heterogeneity in cellular mechanisms affecting prion propagation and clearance kinetics [ 26, 30].

Indeed, since most birds are likely to have a relapse infection, the low tGSH in old P. relictum infected birds can be a result of a more rapid decline of the antioxidant defences (or indirectly via degradation of other cellular mechanisms affecting GSH synthesis) compared to uninfected ageing birds.

Although some common genetic modifiers have been identified among these models, many of the underlying cellular mechanisms affected appear to be disease-specific, despite the shared feature of protein misfolding/aggregation (3, 24).

SIRT1 is involved in a number of cellular regulation mechanisms affecting cellular lifespan, stress resistance, apoptosis and cell metabolism [ 12].

These results indicate that MT is a part of cellular adaptive mechanisms affecting the magnitude and progression of toxic insults from metals such as Cd as well as from organic chemicals such as CCl4.

In the present study, we investigated the functional consequences of SPAST mutations in ONS cells derived from patients with adult-onset HSP but with a variety of SPAST mutations, with the aim of identifying common molecular mechanisms affecting cellular functions.

One of the cellular mechanisms that affect population is believed to be the changes at their genomics level (Laikre et al., 2016; Petersen et al., 2016).

Given the wide spectrum of the cellular mechanisms potentially affected by anisomycin, it is important to note that this drug showed no observable toxic effect on newborn cells.

Here, we present a novel single cell based system, using the DR5 promoter, to address cellular mechanisms that affect cellular auxin homeostasis and ultimately auxin signaling.

Our results describe novel cellular mechanisms that affect genomic instability, sensitivity to DNA-damaging agents, and the migration of tumor cells by reciprocal regulation between DNA-PKcs and Snail1.