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To investigate the cellular mechanism underlying the shaft-to-spinous synapse transition, we designed live imaging experiments to directly observe the dynamics of shaft and spinous synapses on developing dendrites.
To understand the cellular mechanism underlying bone defect healing in the context of tissue engineering, a reliable, reproducible, and standardized load-bearing large segmental bone defect model in small animals is indispensable.
Collectively, the evidence presented above supports the notion that binding to TSPO and the subsequent synthesis of neurosteroid, maintenance of hippocampal morphologic and functional plasticity, and preventing HPA axis dysfunction, may account for the profound molecular and cellular mechanism underlying the antidepressant-like effect of YL-IPA08.
The cellular mechanism underlying the inhibitory effect of mu-opioids remains to be determined.
Although both animal and clinical studies supported its role as a memory enhancer, the molecular and cellular mechanism underlying Bacopa's nootropic action are not understood.
Recently, the Montell group revealed the cellular mechanism underlying an early childhood neurodegenerative disease, mucolipidosis type IV, providing a novel strategy for treating this disease.
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DOI: http://dx.doi.org/10.7554/eLife.12002.007 Next, we investigated the molecular and cellular mechanisms underlying the mechanical hypersensitivity of Eif4ebp1-/ mice.
But the cellular mechanisms underlying these commonalities have remained stubbornly complex.
Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness.
To investigate cellular mechanisms underlying jitter, we simulated SV release in single PF-MLI varicosities.
This course covers aspects of the fundamental molecular and cellular mechanisms underlying various human diseases.
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