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It is known that temperature greatly affects cellular mechanical properties such as viscosity.
To analyze the effects of fixative on cellular mechanical properties, we firstly measured adhesion force of fixed and unfixed lymphocytes (Fig. 3a, b).
Previous studies have revealed that changes of cellular morphology may also lead to changes of cellular mechanical properties in some cases [10, 24].
Cellular mechanical properties have emerged as central regulators of many critical cell behaviors, including proliferation, motility, and differentiation.
The properties of eccentric muscle actions which lead to this protective effect remain to be elucidated but are thought to include cellular, mechanical and neural adaptations.
Growing number of literatures suggested that odontoblasts, secondary to its primary role as formation of tooth structure, might function as a cellular mechanical transducer in teeth.
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Relative cell content, distribution, and inter-cellular mechanical and electrical coupling change during development, and in physiological or pathological remodelling of the myocardium.
It does so because bones possess cellular mechanisms wherein external mechanical loads are sensed.
If we can demonstrate in an appropriate assay system that the response is direct we open the possibility of revealing the cellular mechanisms that links mechanical stimulation with gene regulation.
DOI: http://dx.doi.org/10.7554/eLife.12002.007 Next, we investigated the molecular and cellular mechanisms underlying the mechanical hypersensitivity of Eif4ebp1-/ mice.
Even though, signaling response does not always reflect actual cellular and mechanical changes, the studies that report them also report cellular and/or mechanical response in conjunction (Tables 2, 3, 4, 5), with in the majority of the cases showing corresponding in- or decreases.
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