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Alterations at cellular machineries governing those processes are frequently observed in cancer cells including HCC.
Protein modifications by intricate cellular machineries often redesign the structure and function of existing proteins to impact biological networks.
The findings presented in this Select highlight innovative ways to both dissect and reconstruct various cellular machineries and components.
Nanotechnology provides novel tools to manipulate cellular machineries and possess the ability to bring paradigm shift in how cancer is being currently imaged or treated.
Tight correlations between mRNA distribution and subsequent protein localization and function, indicate major roles for mRNA localization in nucleating localized cellular machineries.
HIV-1 manipulates cellular machineries such as cyclin dependent kinases (cdks) and their cyclin elements, to stimulate virus production and maintain latent infection.
Bacteria have evolved complex, multi-component cellular machineries to carry out fundamental cellular processes such as cell division/separation, locomotion, protein secretion, DNA transcription/replication, or conjugation/competence.
The transcriptional apparatus is one of the most complex cellular machineries and in order to fully appreciate the behavior of these protein nucleic acid assemblies one has to understand the molecular details of the system.
Current evidence shows that autophagy is required for ER stress-associated apoptosis and mitochondrial turnover, thus may mediate the integration of the insulin/IGF-1 and mTOR signaling pathways with other cellular machineries in regulating longevity (Meijer and Codogno, 2009; Vellai, 2009).
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Viruses hijack the cellular machinery and replicate within the cell of the host.
They watched as the virus hijacked the cellular machinery and began reproducing itself.
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