Sentence examples for cellular lifespan from inspiring English sources

Dang, W. et al. Histone H4 lysine 16 acetylation regulates cellular lifespan.

Vermulst, M. et al. Transcription errors induce proteotoxic stress and shorten cellular lifespan.

The catalytic subunit of telomerase, hTERT, has been used to maintain telomere length and consequently extend cellular lifespan.

The current states of research in these areas are reviewed as they relate to tissue engineering and the cellular lifespan.

The selection of a proper cell source and attention to cellular lifespan are important factors that dictate the success of a vascular graft.

To test this hypothesis, the effectiveness of telomerase expression to extend cellular lifespan was assessed in a model of human vascular tissue engineering.

In the context of normal human cells, the enzyme can extend cellular lifespan without causing cancer-associated changes or altering phenotypic properties.

In addition, the book describes our current knowledge on checkpoints that limit cellular lifespan (senescence) and survival (apoptosis, crisis) in response to telomere dysfunction.

Thus, while telomere length plays a role in cellular lifespan in cultured human cells, it is not a major factor in determining organismal lifespan.

The effects of such activation are significant given that a ~2 fold proteasome activation has been shown to confer cytoprotective effects to human fibroblasts against oxidative stress and to extend their cellular lifespan [26].

CMPD16 was not as effective in cellular lifespan extension as SB203580, however, suggesting that, although MK2 is a downstream kinase involved in cell cycle arrest, other p38 targets may play a role.