Sentence examples for cellular life span from inspiring English sources

Treatment with the p38 inhibitor SB203580 increased the growth rate and the cellular life span of primary WS fibroblasts, and rescued their senescent-like morphology [3].

Treatment with the p38 inhibitor SB203580 increases the growth rate and the cellular life span of primary WS cells to within the range seen for normal fibroblasts, and rescues their senescent-like morphology [3, 4].

Elevated levels of intracellular ROS through hydrogen peroxide treatment, or deficiency of ROS scavenging enzymes such as superoxide dismutase (SOD1) knockdown, has been shown to induce premature senescence and reduce cellular life span [3], [4], [5].

Telomeres are responsible for regulation of cellular life span.

Alterations in telomere biology both suppress and facilitate malignant transformation by regulating genomic stability and cellular life span [ 31].

In the absence of exogenous genotoxic stress, Necdin has no effect on normal cellular life span in human cells.

Here, I have discussed evidence that rDNA has overlapping roles with the telomere regarding cellular life spans.

As opposed to glucose and ethanol and, possibly, acetic acid, glycerol does not elicit adverse effects on cellular protection and life span suggesting that the Tor1/Sch9-regulated glycerol biosynthesis results in the removal of pro-aging carbon sources [ 11].

These cell lines possess a notable ability to recapitulate the clinical stages of disease from which they were derived [12], [13] and have been characterized with respect to tumorigenicity and metastasis [14] [17]; cellular growth characteristics including life span, growth factor dependency, anchorage-independent growth [12]; and pigmentation and morphology [18].

Computational analysis suggest that, on the average, proteins in the bacterial cytosol are more aggregation prone than those in the human cytosol [30], which is in agreement with the hypothesis that organisms with simpler cellular organisation and shorter life span have, as a trend, higher aggregation propensities [24].

In other words, chronic cellular stress may prolong life span by either activating repair mechanisms or by causing cell adaptation or both [ 1- 3].