Sentence examples for cellular level resulting from inspiring English sources

According to Wikipedia, the MoA describes 'a functional or anatomical change, at the cellular level, resulting from the exposure of a living organism to a substance'.

Aging represents a biologic attrition at the cellular level resulting in decreased reserve capacity and ability to perform normal functions occurs throughout an organisms' life span increasing the likelihood of death.

The second term is a process that is carried out at the cellular level resulting in the formation, arrangement of constituent parts, or disassembly of any organelle within a cell.

Even with high binding affinities, however, there is a finite probability that individual oligomers will, from time to time, escape such protective mechanisms and interact with cells to initiate the cascade of calcium influx, ROS production, and caspase-3 activation in astrocytes and neurons on a local cellular level, resulting in altered synaptic function.

A series of coordinated interactions between the two major groups of receptor molecules in the mammalian innate immune system, the TLRs and NLRs, lead to comprehensive detection of toxins and 'stress' signals at both intracellular and extra-cellular levels, resulting in a specific response being mounted against a range of pathogens.

This would establish a tissue-level significance of the previous cellular level results suggesting that altered Ca2+ homeostasis could affect Na+ channel function.

The early response at the cellular level results partly from cell damage, and corresponds partly to adaptive processes that initiate changes in the metabolism and structure of the cell that allows it to function under low water potential [ 3].

This suggests that the swd p75fm and trpm7 b508 mutations impair the function of Trpm7 in controlling the cellular Mg2+ level, resulting in reduced size of exocrine pancreas.

Recent studies also implicated ROS-mediated oxidative stress to promote tumorigenesis Herein, we found that squamous cell carcinoma progressed earlier into EMT that was conditional on elevated cellular ROS level resulting from TAK1 deficiency.

AMPK is a eukaryotic heterotrimeric (α, β and γ) protein kinase activated in response to environmental stresses such as glucose deprivation and hypoxia, which produce changes in cellular ATP levels, resulting in phosphorylation of AMPK at Thr 172.

For example, Arabidopsis plants with silencing of GLB1 (class I nsHbs) exhibit increased cellular NO levels, resulting in modified development with stunted organs, loss of apical dominance and late flowering (Hebelstrup et al. 2006; Hebelstrup and Jensen 2008).