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Human genetic studies, as well as studies examining structural changes at the cellular level, have converged on glutamatergic synapse formation, function, and maintenance as common pathophysiologic substrates involved in both disorders.
Studies of the effects of radiation at the cellular level have generally been carried out by exposing cells randomly to the charged-particle tracks of a radiation beam, Recently, a number of laboratories have developed techniques for microbeam irradiation of individual cells.
However, no studies at cellular level have suggested an interaction between T. cruzi and HIV-1 to date.
Although the KKDC peptide has been shown to physically interact with heparin and HS [29], binding and localization at the cellular level have not been so far demonstrated.
Several experimental studies investigating the influence of glucose, insulin, and osmotic stress on the immune system on a cellular level have been undertaken [ 14- 19].
Characterizations of plant penetration by oomycetes at the cellular level have focused mostly on Phytophthora spp. Entry into the host is mediated principally by a specialized cellular structure called the appressorium [ 4– 8].
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Fabrication of functional DNA nanostructures operating at a cellular level has been accomplished through molecular programming techniques such as DNA origami and single-stranded tiles (SST).
Our understanding of chronic inflammatory and neuropathic pain at the molecular and cellular level has developed at an extraordinary rate in recent years.
But how stress accomplishes its sinister work on a cellular level has remained mysterious.
The skeletal site-specific influence of multiple genes on bone morphology is recognised, but the question as to how these influences may be exerted at the molecular and cellular level has not been explored.
Furthermore, the lack of good in vitro MuHV-4 latency/reactivation systems with which to dissect mechanisms at the cellular level has made some parallels with EBV and KSHV hard to draw.
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