Sentence examples for cellular level due from inspiring English sources

Bohm et al. [31] suggested that the short loading duration during jumping constrains the transduction of the mechanical stimulus to the cellular level due to the viscosity of the tendinous tissue and, therefore, may not be optimal to facilitate adaptive responses of the tendon.

This local oxygen consumption limitation may be due to two different but cumulative mechanisms: (a) a local supply-demand dependency on low flow or inadequate flow conditions or (b) a low oxygen extraction at the cellular level due to mitochondrial dysfunction and/or alteration of oxygen diffusion (interstitial edema) [ 23, 50].

Circadian genes have been shown to function as oncogenes or tumor suppressors at both the systemic and cellular levels due to their roles in cell proliferation, cell cycle regulation, apoptosis and DNA damage signaling pathways [8], [9].

Discussion/conclusion: First experiments implied radiolabeled BODIPY-C16 is a promising BAT PET tracer with the opportunity to resolve its metabolic character on a sub-cellular level due to its dual-modality.

The last decade has witnessed an unprecedented explosion of biological knowledge and large data sets acquired for many signalling processes at the cellular level, largely due to the development of sophisticated and high-throughput biochemical techniques in proteomics and other omics.

The relative combination of chemotherapy, radiotherapy and methylation status to outcome has not been well investigated at the cellular level, presumably due to the technical difficulties in creating a representative cell line model.

It is possible that the reduced protein counts indicated by the fluorescence measurements reflect a reduction in the cellular protein level due to biological differences in the structure of the MTOC.

DE in HD is thought to reflect both cell-intrinsic changes in gene expression (i.e. changes in gene expression induced by the mutant huntingtin protein), as well as changes at the cellular population level due to neuronal cell death and subsequent astrogliosis [ 14, 17, 20].

Pathological increases in cellular NO levels due to an increase in iNOS expression or overactivation of eNOS and nNOS result in the formation of peroxynitrite (ONOO-) radical [67].

Using malignant keratinocytes, this study indicated that cell proliferation depended on the reduction of cellular T3 levels due to D3 activity, which effectively blocks both T3-stimulated differentiation and inhibition of progression of the cell cycle.

The differences we observed may possibly be explained either by changes in leucocyte populations expressing varying amounts of XIAP, and/or increases in cellular XIAP levels due to cell division or stimulation with G-CSF or GM-CSF.