Exact(4)
Our results demonstrate that Riluzole interacts with the Nav1.6 channel, more specifically in the key residues TYR 1787, LEU 1843 and GLN 1799, suggesting possible cellular implications driven by these amino acids on Riluzole Nav1.6 interaction, which may serve as an important output for a more specific and experimental drug design therapy against ALS.
However, the cellular implications of Ca2+ signalling by these channels are not known.
Lysine methylation of histones and non-histone proteins has emerged in recent years as a posttranslational modification with wide-ranging cellular implications beyond epigenetic regulation.
The full cellular implications for these changes in gene expression are difficult to interpret, but some inferences can be made in respect of the stress phenotypes we have observed in this study.
Similar(56)
The observation that most pS/pT in proteins with multiple sites reside in clusters raised the question on the cellular implication of the phenomena.
Based on our results and due to the cellular biomechanical implications of the involved tensile and compressive forces, we developed a global mechanistic scenario that predicts epithelial folding during embryonic inversion in V. globator.
Although ITGA9-ITGB7 is unlikely to be a widely expressed integrin and appears to be the result of "compensatory dimerization" occurring in the context of little/no ITGB1 expression, the data indicate that ITGA9-ITGB7 functions as an ADAM binding partner in certain cellular contexts, with implications for mammalian fertilization and integrin function.
Lastly, functional and pathway analysis of ortholog genes were conducted to understand cellular and physiological implications.
A functional screen in yeast has expanded the list of genes required for Cu-dependent fitness, revealing a complex cellular system with implications for human health.
More recently PPARgamma emerged from a role limited to metabolism (diabetes and obesity) to a power player in general transcriptional control of numerous cellular processes, with implications in cell cycle control, carcinogenesis, inflammation, atherosclerosis and immunomodulation.
The data shed light on cellular mechanisms and have implications for some neuro-tissue engineering strategies.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com