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He adapted and perfected cellular imaging methods to better visualize the process through which adaptive immunity develops.
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Recent advances in fiber-optic technologies have led to the development of several novel sub-cellular imaging methods in vivo [ 8].
Therefore, in our present study, we analysed the expressions of TNF-α and NF-κB as an upstream event of nanoparticle-induced inflammatory response in macrophage cells using a high-content cellular imaging cytometry method.
This study highlights the need to characterise the long-term profile of cerebral ischaemia, and points to confounding image contrast at later timepoints that must be overcome in order for iron oxide-based cellular imaging to be a viable method of cell tracking.
In this review, we summarise and discuss recent methods developed for cellular imaging of G-quadruplexes, and the application of experimental genomic approaches to detect G-quadruplexes throughout genomic DNA.
Our screening method, based on cellular imaging cytometry, provides simultaneous monitoring of cellular events and facilitates quantitative multivariate cellular analysis with the elimination of false positive errors, as it provides high-spectral resolution among the fluorophores.
Fluorescence imaging also has the advantage of more rapid image capture (milliseconds) than radioactive imaging methods.
Magnetic resonance methods that employ the F nucleus for cellular imaging or molecular structure and dynamics investigations become increasingly important for both in vitro and in vivo systems. 1 Fluorine is hardly encountered in biomolecules and therefore provides excellent bioorthogonality.
Our optical in vivo imaging methods provide a great opportunity to investigate the cellular components of the arthritic process and provide direct evidence for the importance of sensory immune interactions.
The key advantage of PET and SPECT over other imaging methods lies in their ability to measure nanomolar concentrations of cellular receptors or enzymes without saturating the system under study.
Molecular imaging modalities can assess biologic processes at the molecular and cellular level, which is useful for early detection of cancer and complements traditional anatomic imaging methods [ 30].
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CEO of Professional Science Editing for Scientists @ prosciediting.com