Sentence examples for cellular focus from inspiring English sources

Therefore, we performed tissue-specific rescue experiments to determine the cellular focus of action.

The reason for this fundamental difference in cellular focus remains poorly understood.

However, MSA is distinct from other α-synucleinopathies in a number of respects, not least the disparate cellular focus of α-synuclein pathology.

Hence, these disparities highlight that unique pathophysiologies of α-syn dysfunction are likely to operate in MSA and PD, which would explain the fundamentally different cellular focus of pathology in each disease.

The primary cellular focus of action was macrophages, and genes induced by the transcription factor NF-κB were key molecular targets (Nicodeme et al., 2010; Belkina et al., 2013).

Despite this potential complexity, Tank and colleagues found that neuronal re-expression of DAF-16 in daf-16 daf-2 daf-16 daf-2ts was sufficient to rescue the doubled onset of neuronal defects observed in daf-2 single mutants, identifying neurons as the cellular focus of DAF-16-mediated control of neuronal aging.

The lesions characteristically had a multipatterned architecture with tumor cells focally assuming a lacelike/sievelike growth pattern in the more stroma-rich areas of the tumor and a vague fascicular growth pattern in the more cellular foci.

Cells were cultured for two weeks and cellular foci were photographed and foci number and area determined by an investigator blinded to the status of the samples using Metamorph software.

It is thought that excess p85α may exert these effects by sequestration of IRS-1 and PI3K enzymatic activity into inert cellular foci incapable of PI-3, 4, 5-triphosphate (PIP3) generation [27].

Multifocal inflammatory cellular foci were observed in the kidney of DM mice).

Cellular foci, including P-bodies, have been shown to be highly dynamic.