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He was interested in developing drugs to block a family of cellular enzymes implicated in several cancers.
Other agents (idoxuridine) are activated by cellular enzymes, so these have less specificity.
These contain DNA, and are connected by microfluidic channels to a bath of cellular enzymes.
Camptothecin is also released quickly when it encounters cellular enzymes called esterases.
A platinum catalyst mimics the activity of cellular enzymes that break down glucose to generate ATP, the cell's energy currency.
The normal protein conformation can be degraded rather easily by cellular enzymes called proteases, but the prion protein shape is more resistant to this enzymatic activity.
The 3-HPA toxicity has been shown to be related to the inactivation of cellular enzymes, in particular, DhaB and KGSADH33,66,67.
Food is broken down in a series of steps by cellular enzymes (proteins that catalyze the conversion of compounds called substrates) into products with a different biochemical structure.
Protein kinases are cellular enzymes that attach phosphate groups to other proteins as part of a sophisticated cellular communication and signaling system.
Certain cellular enzymes may be less active, and thus more time may be required to carry out chemical reactions.
Protection of crRNA ends by phosphate backbone modifications have been shown to improve editing efficiencies, suggesting that degradation by cellular enzymes can reduce the half-life of the complex within the cell.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com