Sentence examples for cellular defects that from inspiring English sources

We observed that gametes no longer contained any of the cellular defects that were present in the aged precursors (Figure 2).

The zebrafish is a compelling vertebrate model for understanding cellular processes in the context of the developing embryo and for analysis of cellular defects that lead to diseases such as cancer.

However, the expansion procedure is known to exhaust the stem cell pool causing cellular defects that promote apoptosis and disrupt homing to the bone marrow.

Despite the well-characterized biochemical consequences in these individuals, the underlying cellular defects that contribute to CDG are not well understood.

In addition to that, R103W protein is prone to aggregate in vivo due to reduced stability, whereas P486S showed enhanced interaction with J-proteins, thus remarkably recapitulating the cellular defects that are observed in human PD variants.

To better understand the cellular defects that occurred during pollen development in the MT, a comparative proteomic approach was conducted, and 62 differentially expressed protein spots were identified between the PGMS MT and WT anthers at three developmental stages.

Researchers have found a cellular defect that can impair the body's ability to handle high glucose levels, pointing the way to new treatments for diabetes.

Rather, Sp2-deficiency causes a general cellular defect that precludes normal progression of development resulting in early embryonic lethality.

Another cellular defect that has been observed in mouse MCM hypomorphs is an overall decrease in cellular proliferation, possibly associated with a depletion of stem cell populations [45,62].

Periodic monitoring of patients hospitalised in key services (that is, oncology, transplantation units, critical care units) could help to identify specific humoral or cellular immunity defects that could be addressed by implementation of prophylactic measures, such as administration of intravenous immunoglobulin (IVIG) or proper cover with broad-spectrum antibiotics.

We predict that future in vitro studies will help to elucidate not only the precise cell types affected in these disorders but also the cellular and molecular defects that contribute to the diseases.