Sentence examples for cellular context that from inspiring English sources
These observations suggest that IGF-1 may be an EWS-FLI-1 target in a permissive cellular context that may constitute an origin of ESFT.
These studies highlight the importance of the timing of fusion transcript expression during cell differentiation and the highly restricted cellular context that is permissive for its oncogenic properties.
Taken together, these data suggest that MSC provide a cellular context that permits SYT-SSX to induce a transcriptional profile similar to the one that characterizes synovial sarcoma but that among individual MSC populations, some are more permissive than others for these transcriptional changes.
Therefore it is important to identify the appropriate cellular context that enables productive H-RAS transformation.
Hence, lymphoma cells can also display the cellular context that allows initiation of Xist-mediated gene silencing.
It is inherent in the concept of an ancestral sequence that a true ancestor would have been functional in the cellular context that existed at the time.
Our results expand knowledge of Ub processing enzyme functions in cellular contexts that currently depends largely on using recombinant enzymes and substrates.
This raises the question of whether the failure to observe a particular α-β heterodimer is indicative that the α-β combination cannot form, or that the α-β combination is a rare occurrence in nature or in the cellular contexts that have been examined.
We demonstrated a systems approach to infer the combinatorial GRNs utilized by miR-K12-11 miR-K12-11 miR-K12-11that are close to KSHV infecellular vivo.
Its precise expression control in development and differentiation make it an interesting marker for certain cellular contexts that are associated with epigenetic transitions and potentially, changes in cell identity.
It has not been proven however that mutant ASYN can induce CMA impairment in a cellular context, or that this effect could lead to lysosomal dysfunction.
