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The hypothesis provides a framework in which the stability of communicating cellular communities (bacterial consortia, host-pathogen ensembles etc).
In the next level, parts and devices are combined into functional cells and further into cellular communities.
Cancer is a heterogeneous disease consisting of different cellular communities which engage and adapt with the microenvironment to survive and proliferate.
Nevertheless, this approach is very convenient for modeling at the cell population level, as it allows to track changes in individual cells and to study the emergent properties of cellular communities.
The applications that synthetic biologists are pursuing are diverse and range from optimizing the biosynthetic capabilities of cells to produce fuels and drugs, to harnessing the ability of cells to act as environmental biosensors, to manipulating cellular communities and tissues for medical purposes [ 1, 2].
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The Mobile Girl can convert pad strokes to kanji faster than should be humanly possible, and rates her standing in her cellular community according to the amount of numbers in her phone's memory.
This gradient in cell phenotypes largely mimics the cellular community of the native enthesis and is therefore a promising first step toward the regeneration of tendon-to-bone insertion.
This opened the door to a new emergent level of complexity, the tightly organized cellular community named tissue with entirely new possibilities comprising simultaneous response to external cues resulting in significantly improved resistance to hostile living conditions.
This makes sense, as fine-tuning and integrating diverse signals need to be coordinately transferred to the respective transcriptional response which is substantial for fine grained signaling homeostasis of normal cells to co-ordinate their signals in accordance to their cellular community in the tissue.
Cavalier-Smith reasoned that they probably existed in the pre-cellular communities too.
These results demonstrate roles for self-organization and aggregation in persistence of multi-cellular communities, and also illustrate a role for the techniques of synthetic biology in elucidating fundamental biological principles.
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CEO of Professional Science Editing for Scientists @ prosciediting.com