Sentence examples for cellular background of from inspiring English sources
Our data indicate that in the particular cellular background of EC cells p53 seems to act primarily as a pro-apoptotic factor.
Autophagy may precede apoptosis or be induced simultaneously depending on the genetic context and cellular background of the cells.
The first is the shortest and serves as an introduction to the other two, by describing the cellular background of melanoma pathogenesis that is necessary to understand the subsequent development of therapies.
To go back to histological findings cHL and NLPHL both show a similar mixed cellular background of non neoplastic bystander cells which most likely provide the tumor cells of both entities with an analog pattern of paracrine stimuli.
This corroborates the importance of considering the influence of the cellular background in the interpretation of EWS/FLI1 target gene studies.
Antigen surface expression density, the respective function in a given cellular background, the level of internalization and, as shown for monocytes, the activation status may govern susceptibility to HM1.24-ETA′ and other immunotoxins.
Thus consideration of the cellular background is crucial for evaluation of any results.
Multiclassifier combinatorial proteomics and the data sets described here open the door to the identification of all functional components of mitotic chromosomes despite the adventitious binding of cellular background proteins during mitosis.
As expected, in both cellular backgrounds expression of NES-hTERT significantly increased basal levels of mtDNA damage (Fig. 4C), suggesting that mitochondrial dysfunction is also amplified in the cancer cells by expression of the mutant protein.
According to the known broad cellular distribution of ROCKII, cellular background staining was high.
Our data provide evidence that in mini-EBV genomes DS is the predominant site of ORC-binding and pre-RC assembly and also the preferred initiation start site regardless of the cellular background (Figs. 2 to 6 and S1, S2).
