Sentence examples for cellular background from inspiring English sources

This approach generated mosaic genetic mutations within a wild-type cellular background.

Future studies should aim to investigate the cellular background explaining such differences, as well as how they may relate to the selective vulnerabilities of specific populations of neurons in different diseases.

The designed inhibitors are specific for the sensitized kinase in a cellular background where the wild-type kinase has been inactivated.

Here, we have systematically assessed the impact of differential cellular protein complement (and cellular background), signalling kinetics and receptor species on our previous descriptions of biased agonism at MOP by several opioid peptides and synthetic opioids.

In human HOS cells, but not in hamster BHK21 cells, replicated TBEV RNA was found also associated with the marker Giantin for the Golgi indicating differences according to the cellular background.

Fig. 2 a Photomicrograph of the cerebral biopsy showing numerous mononuclear Hodgkin cells and multinucleated Reed Sternberg (HRS) cells in a cellular background (arrows) (haematoxylin-eosin; original magnification ×200).

According to the known broad cellular distribution of ROCKII, cellular background staining was high.

Under different genetic and cellular backgrounds, peptides have been shown to function as potent vehicles for splice correction, and their therapeutic benefits have reached clinical trials and patenting stages, emphasizing the use of regulatory peptides as an exciting therapeutic tool for the treatment of different genetic diseases.

Thereby, basal autophagy as well as induced or inhibited autophagy can be compared using different cellular backgrounds.

Our model has the advantage of permitting systematic statistical analyses of synergy employing generic laboratory cellular screening experiments involving a vast array of genetic cellular backgrounds.

As expected, in both cellular backgrounds expression of NES-hTERT significantly increased basal levels of mtDNA damage (Fig. 4C), suggesting that mitochondrial dysfunction is also amplified in the cancer cells by expression of the mutant protein.