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Microtubules are important components for establishing positional information, and are required to establish a cellular axis and to position the nucleus.
The cytokines produced by Th1/Th2 cells mediate osteoclast formation and function and this cellular axis has been shown to be dysregulated in several bone pathologies [ 2].
Because spindle orientation relative to the cellular axis occurs in both colonial and noncolonial S. rosetta cells, spindle orientation is likely to involve internal marks imposed by the cell's polarity rather than cues from neighboring cells.
Because this mode of spindle orientation relative to the cellular axis occurs in both colonial and non-colonial S. rosetta cells, it must involve internal marks imposed by the cell's polarity rather than cues from neighboring cells".
Thus, while integrin α5 is required to generate the proper geometry of the node, it is not essential for the establishment of the anterior posterior embryonic or cellular axis.
The appropriate subcellular localization of signalling receptors and adhesion molecules along the cellular axis of migration is critical for directing neutrophils out of the vasculature to sites of inflammation.
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In the spheroidal colonial and multicellular volvocine species, the cellular anterior-posterior axis is different from the anterior-posterior axis of the whole organism.
This paper proposed an improved cellular automaton with axis information, defined as the Multi-axle Single-cell Cellular Automaton (MSCA), for the precise micro-simulation of random traffic loads on bridges.
These signalling pathway intermediates are found in diverse cellular regulatory signalling axis, including cell proliferation, survival, cell cycle, cytoskeletal functions, and transcription.
It has been described that the CXCR4-SDF-1 axis regulates cellular trafficking [ 23] and that ASC produce and secrete SDF-1 [ 24].
The UbcH10-expression pattern in cancer supports the notion that this regulatory axis controls cellular proliferation and that its abrogation leads to carcinogenesis.
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