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this mode of establishing cellular asymmetry.
Life as we know it requires cellular asymmetry.
McMurray MA, Thorner J (2009) Septins: molecular partitioning and the generation of cellular asymmetry.
Cells of many tissues acquire cellular asymmetry to execute their physiologic functions.
Aw WYih, Devenport D. Planar cell polarity: global inputs establishing cellular asymmetry.
Caulobacter crescentus is a premier model organism for studying the molecular basis of cellular asymmetry.
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In this review, we discuss apparent similarities and differences in the mechanism that controls PCP as it has been adapted to a broad variety of morphological cellular asymmetries in various organisms.
How the Ft-Ds-Fj system might generate cellular asymmetries that regulate Dachs localization is unknown.
Reviewer 2 noticed subtle differences in the modelled cellular asymmetries across the tissue presented in Figure 5A.
Hence, the overall consequence of a Fj gradient and free movement of Ft and Ds within cells is the generation of cellular asymmetries of Ft and Ds distributions.
Unless the authors can attempt to include these mechanisms and show that they can be significant factors in generating the high cellular asymmetries, the mystery, in my opinion, still exists.
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