Sentence examples for cellular and pathologic from inspiring English sources

Styren, S. D., Civin, W. H. & Rogers, J. Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain.

The ability of TG2 to regulate most of these various cellular and pathologic functions has been linked to its role in TGF-β expression and bioactivation in fibroblasts, breast and ovarian cancer cells, and renal epithelial cells [ 22, 50, 53- 55].

For this reason, and because of the ease of use and reproducibility that can be achieved, these imagable models provide ideal systems for determining anti-metastatic effects of cancer drugs and therapeutic regimens and is well suited for investigating the molecular, cellular and pathologic basis for metastasis to specific organs and tissues.

Protein tyrosine phosphatases (PTPs) play a fundamental role in regulating diverse proteins that essentially participate in every aspect of cellular physiologic and pathologic processes (Zeng et al, 1998).

RAF kinases are serine/threonine kinases whose activity is modulated by growth factors and that play a central role in normal and pathologic cellular processes, including development, cell regeneration, cell senescence and cancer [16].

The TGF-β family has been extensively studied and is known to be involved in a variety of cellular functions, both physiologic and pathologic [ 28].

Subsequent biochemical and genetic studies provided evidence for the activity of MLL1 in a wide range of physiologic and pathologic cellular processes, including cell proliferation and differentiation, through the regulation of Hox and non- Hox gene expression [102]– [104].

The importance of DNA methylation in normal and pathologic cellular processes has stimulated a growing interest in how DNA methylation suppresses gene expression, and in examining how changes in methylation patterns affect gene expression.

It is not a surprise that also P-TEFb is an miRNAs target and that several miRNAs are involved in the regulation of P-TEFb availability in different physiologic and pathologic cellular models.

TCTP is a multifaceted protein which has been implicated in a number of key cellular processes, both physiologic and pathologic, such as development, immune response, cell cycle, cell proliferation and growth, cell division, cytoskeleton activity, protein synthesis, and calcium binding [ 28, 29].

Gene expression modulates cellular functions in both physiologic and pathologic conditions.