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To reliably detect the Raman signal in a format appropriate for cellular analyses, we developed a automated Raman scanner (Intel Raman BioAnalyser IRBABA) that is suitable for detecting Raman signals (Figure 2A).
Using biochemical, mutation, and cellular analyses, we characterized important domains involved in the functionality of a RNA-binding protein in RNA splicing.
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Tetrazolium reduction is a ubiquitous property of cells, enabling a simple colorimetric cellular assay technology to be multiplexed into thousands of different assays and facilitating detailed cellular analyses in what we term Phenotype MicroArrays [3] [6].
We have carried out morphological and cellular analyses of cleavage-stage chick embryos covering the first half of pre-ovipositional development, from Eyal-Giladi and Kochav stage (EGK-) I to EGK-V.
We demonstrate that standard FC methods for cellular analyses fail to capture the vast majority of BM SECs and CARcs, which are strikingly abundant.
We approach this using a combination of molecular and cellular analyses, mutant mouse models, and genetic screens in zebrafish.
Cytometric, RNA profiling and proteomic platforms will be used in these serological and cellular analyses.
S.L. generated P. falciparum strains, performed the molecular and cellular analyses with A.S.P.Y. and performed humanized mouse experiments.
To explore the plaque-promoting signalling pathways associated with YAP and TAZ activation, Wang and colleagues conducted cellular analyses, including the analysis of messenger RNA sequences.
How DAXX selectively recognizes H3.3 over the canonical H3.1 is now revealed by the crystal structure of DAXX in complex with H3.3 H4, along with biochemical and cellular analyses.
Availability of tumor tissue pre- and post-nivolumab dosing and from additional patients who did not receive nivolumab allowed the evaluation of changes in the tumor immune microenvironment using multiple molecular and cellular analyses.
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