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Our cellular analyses suggest that maximizing efficacy in (NZB × NZW F1 mouse models requires not only targeting the components of MZ B cells but also depleting other B cell subsets such as naive/activated B cells.
Our published molecular and cellular analyses suggest that two commonly-occurring tumour-associated "gain-of-function" mutants (R175H and R273H respectively) have no effect on expression from the PLK1 promoter, at least in the context of promoter-reporter (luciferase) assays [ 30].
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Morphological and cellular analyses suggested that GNS4 positively regulates grain size by promoting cell elongation.
Immunofluorescence microscopic and cellular fractionation analyses suggested that Eos1 localizes in the endoplasmic reticulum membrane.
Cellular analyses indicate that D2/SMG11 controls grain size by promoting cell expansion.
Rosette formation is only a kinematic description of cell-shape changes that reflect a common geometric constraint but not necessarily common cellular mechanisms; however, our analyses suggest that rosette formation in C. elegans bears common features with known mechanisms and concepts of morphogenesis at the molecular and cellular levels as well as on the whole-embryo level.
Histological and cell proliferation analyses suggest that early cellular events are similar between denervated and innervated limbs, but denervated limbs are incapable of blastema formation because they do not support significant cell proliferation and outgrowth [ 20- 25].
Taken together, these analyses suggest that an array of cellular processes including cell division and growth, protein metabolism, lipid metabolism, and the stress response were modulated in SM muscle by dietary protein restriction.
The change in cellular morphological features and the results of annexin V/caspase 3 analyses suggest that the induction of apoptosis is responsible for Tan IIA-induced U-937 cell death.
Our analyses suggest a generic systems level mechanism of regulation of the cellular signaling network at the transcriptional level.
But these analyses suggest the efforts should be redoubled.
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CEO of Professional Science Editing for Scientists @ prosciediting.com