Sentence examples for cellular adaptations from inspiring English sources

The results are consistent with our hypothesis that hypoxia and acidosis occur frequently in DCIS, and that cellular adaptations confer an adaptive advantage that allows subsequent spread into regions that are normoxic with normal pHe.

Cellular adaptations to sustained hypoxia are in part mediated by hypoxia-inducible factor (HIF).

Mirroring the behavioral outcomes of LDTg inhibition, CSD failed to elicit VTA cellular adaptations.

The cellular adaptations to sustained hypoxia are mediated by hypoxia-inducible factors (HIFs) to regulate downstream target gene expression.

This system circumvents potential cellular adaptations to permanent knock-outs and enables a efficient and highly reproducible knock-down.

These observations set the basis for a neuroanatomical specificity causally linking DA cellular adaptations and maladaptive behaviors to chronic stress.

In striking contrast, selective silencing of LDTg glutamatergic neurons during CSD failed to prevent behavioral and cellular adaptations to stress.

Selective inhibition of cholinergic, but not glutamatergic, LDTg neurons prevents stress-induced cellular adaptations within VTA DA neurons and the appearance of anhedonia and social withdrawal.

However, a clear understanding of how cellular adaptations within delineated neural circuits give rise to depressive-like behaviors is still largely lacking.

This increased cholinergic tone is a prerequisite for the subsequent stress-induced cellular adaptations of VTA DA neurons and the appearance of social aversion and anhedonia.

This set of data indicates that direct LDTg stimulation of VTA neurons paired with a short-lived stress is sufficient to promote behavioral and cellular adaptations, and that this effect requires activation of VTA nAChRs.