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By efficiently enhancing downstream signaling of HGF pathways, the cellular activities and behaviors were activated to contribute to LG branching morphogenesis.
JNK2 and p38α are closely related mitogen-activated protein kinases that regulate various cellular activities and are considered drug targets for inflammatory diseases.
Ligands that are categorized in the YES/NO group promote the general proliferation of cellular activities and the YES/YES group tends to activate the adhesion and migration of related genes.
On the other hand, the function of GEF proteins is to activate Rho GTPases, which are important regulators of multiple cellular activities and, most notably, reorganization of the actin cytoskeleton [ 40].
The synthesis, enzymatic & cellular activities and pharmacodynamic effects are described.
These compounds exhibited improved cellular activities and maintained balance between p38α and CYP3A4 inhibition.
However, these studies do not probe cellular activities and the hierarchical cellular structure of the transcriptome to identify the underlying genes regulating a large blanket of downstream targets.
Tyrosine kinases (TKs) play an essential role in regulating various cellular activities and dysregulation of TK signaling contributes to oncogenesis.
The microstructure and mechanical properties of such scaffolds are important parameters to promote further cellular activities and neo-tissue development.
Eukaryotic L10 also exhibits a variety of cellular activities, and, in particular, human L10 is known as a putative tumor suppressor, QM.
Advanced tissue engineering approaches rely upon the employment of biomaterials that integrate biodegradable scaffolds with growth factor delivery devices to better guide cellular activities and enhance tissue neogenesis.
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