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In contrast to murine NKT cells, which were reported to be resistant to cytokine polarization in vivo [36], upon activation with either environmentally instructed dendritic cells (DCs) or DC1 and DC2 antigen presenting cells (APCs), human NKT cells have been shown to undergo polarization into cells with Th1- or Th2-like cytokine production profiles, termed NKT1 and NKT2 cells [37], [38].
In line with this, the CD86+ population overlapped with CD5hiCXCR4lo CLL cells which were reported to comprise recently divided cells based on their incorporation of heavy water in vivo [21].
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The purpose of this study was to determine the mechanism by which glucocorticoids stimulate c-fms proto-oncogene expression in JAR choriocarcinoma cells, which are reported to lack the glucocorticoid receptor.
Interestingly, this nanoconcave structure can be used to enhance light absorption and power conversion efficiency of thin-film solar cells which was reported by us previously [29].
The proinflammatory stimuli is also necessary for diverting the immune response towards protective Th17 cells, which is reported to be important for the rapid recruitment of Th1 effectors to the lungs [34], [35].
Some have gained perhaps certain functional properties of stem cells, which was reported for PC3 [ 42] and DU145 [ 43].
This is despite using their most updated protocol for producing STAP cells, which was reported in Protocol Exchange (Obokata et al., 2014c).
These results differ from daunorubicin induction of nSMase2 in MCF7 cells, which was reported to require the transcription factors Sp1 and Sp3 – which appear to be dispensable in our system.
Then TNF-α was removed through degradation, whereas the second peak was released by activated macrophages, dendritic cells and kupffer cells, which was reported by Nakama T et al[ 24].
As shown in Table 1, the soft coral L. arboreum presented very strong cytotoxicity and selectivity (IC50; 6.5 μg/ml, SI; 6.45) in U937 cells which is reported here for the first time.
To determine the effect of Cab45S binding to GRP78/BiP, we first evaluated the GRP78/BiP expression level in PANC-1 cells, which are reported to have increased protein levels of Cab45S in malignant pancreatic secretome.
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