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In the organoids developed from either hESCs or control iPSCs, the proliferating cells were restricted to 2 3 layers surrounding the lumen of the VZ rosettes.
In normal eyes and eyes with thin or infrequent basal laminar deposits, CD163+ cells were restricted to the inner retina.
The cells in an early embryo were most versatile, they thought, but in adult tissue, even stem cells were restricted to becoming one of the few cell types present in that tissue.
Furthermore, the responses observed in these three above-mentioned cells were restricted to only the time of the stimulation itself.
Regions of TUNEL-positive cells were restricted to white matter tracts, and both the area and density of TUNEL reactivity was increased within anti-CXCR2 treated mice.
Wnt1 tumors showed the converse expression pattern; Conductin-lacZ expressing cells were restricted to a single K14+/K18− layer of the bilayered papillary tumors (Fig. 4D F).
Similar(26)
However, the sources of autologous cells are restricted, cell number is small, and xenogenic cells result in immunological rejections.
Haas, J.D. et al. Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave.
IRF4 expression in Treg cells is restricted to CD44hi cells, is TCR dependent and can be inducibly ablated in Irf4FL/FLFoxp3Cre-ERT2 mice.
Like other stem cells that occur in adult animals, skeletal stem cells are restricted in their ability to generate different cell types.
Since such cells are restricted by their size, improvement in fuel utilization would increase the cell efficiency by several degrees.
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