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The IC50 (concentration of the drug required to kill 50%% of the cells) value of FPCC was 0.65 μg/ml while it was 1.08, 1.56, and 2.35 μg/ml for PCC, PLGA NP, and free CRB, respectively.
The compound was screened for cytotoxicity activity against A-549 cells by determination of CTC50 (concentration of the sample required to kill 50%% of the cells) value by SRB assay.
Blood CD4 cells (cells/mm) within the year of diagnosis and nadir CD4 (the lowest blood CD4 cells value measured since patient's HIV diagnosis), the date of plasma HIV-1 RNA level being below 400 copies and below 50 copies, and any AIDS events, were recorded.
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HPD was calculated from GPW specifically for each ecoregion (i.e. based on mean grid cells values falling within ecoregion).
These are denoted by ωj, and their proportional (to the total number of cells) values by ω*j.
* Percentage transduced cells, values correspond to the highest value listed in the respective manuscript.
Given the FasIII contribution from two adjacent wild-type cells, values from +/+ were halved.
CEP cells' values did not change significantly, but trended downward (P = 0.18) (Fig. 4A).
Generally, we aggregated the data into the quarter-degree cells by averaging the 25 smaller cells' values.
To estimate each cell value of the input structure, we needed more detailed information.
Next, each spatial point in the space is assigned a Hilbert cell value in the grid.
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